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CFTR gene SUBST (cystic fibrosis transmembrane conductance regulator)

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Englisch
For example, there are over 1000 known mutant alleles of the CFTR gene that cause cystic fibrosis.
en.wikipedia.org
In addition, this protein regulates alternate splicing of the CFTR gene.
en.wikipedia.org
Ideally, gene therapy places a normal copy of the CFTR gene into affected cells.
en.wikipedia.org
They started at the crime scene by genetically testing patients with pancreatitis and tracing the process, step by step, to the prime suspect -- that same CFTR gene.
www.post-gazette.com
Human mutations in the CFTR gene might be selected for as a way to survive cholera.
en.wikipedia.org
All disease-causing mutations in the CFTR gene prevent the channel from functioning properly, leading to a blockage of the movement of salt and water into and out of cells.
en.wikipedia.org
During the study, the team conducted genetic testing on nearly 1,000 people, all with idiopathic pancreatitis, and compared their CFTR genes with an equal number of healthy volunteers.
www.post-gazette.com
There are two CFTR gene introduction mechanisms involved, the first use of a viral vector (adenovirus, adeno-associated virus or retro virus) and secondly the use of liposome.
en.wikipedia.org
There are more than 1,900 known mutations in the CFTR gene.
www.theglobeandmail.com
Airway gene therapy works by delivering a correct copy of the CFTR gene into airway cells to rectify the salt imbalance and improve lung health.
theconversation.com

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